Anton van der Merwe is a Professor of Molecular Immunology at the University of Oxford. After completing his Medical degree in UCT, he moved to Sir William Dunn School of Pathology at the University of Oxford in 1991. He is best known for his discovery, with Simon Davis, of the kinetic-segregation mechanism of T cell receptor (TCR) triggering, which is exploited by many other immunoreceptors. Other major discoveries include the importance of size-matching between the receptor/ligand complexes mediating immune recognition.  These discoveries have influenced the development of novel therapies (e.g. bispecific reagents and CAR T cells) that exploit immune recognition. He and Omer Dushek have cofounded a company, MatchBio, to commercialise these discoveries.